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How Long Does It Take for Metoclopramide to Work?

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Leora Rosenthal

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Metoclopramide’s onset depends heavily on how it enters your body. Given intravenously, the drug begins working within one to three minutes. Taken by mouth, it reaches peak blood levels in roughly an hour, though most people notice effects sooner than that because the drug starts acting before concentrations fully peak. A newer nasal spray formulation absorbs within about 15 minutes.

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